ThermOcular AI | AI-Powered Dry Eye Screening

Screen Every Patient for Dry Eye — in 30 Seconds

ThermOcular detects tear film instability during routine exams — using real-time ocular surface cooling.

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No need for dyes or eye contact
Results in under 30 seconds
Objective, reproducible output

Dry Eye Is Common — But Accurate Diagnosis is Poor

Incidence is increasing and many cases are not detected

Problem

— Symptoms are subjective and don't match with clinical signs

— Clinical testing is slow and inconsistent

— Many patients go undiagnosed

— Late diagnosis makes treatment more difficult

Problem

— Symptoms are subjective and don't match with clinical signs

— Clinical testing is slow and inconsistent

— Many patients go undiagnosed

— Late diagnosis makes treatment more difficult

A New Approach to Screening

— Objective measurement in 30 seconds

— Quantifies tear film behavior in real time

— Enables same-visit clinical decisions

— Early detection enables early and better treatment

A New Approach to Screening

— Objective measurement in 30 seconds

— Quantifies tear film behavior in real time

— Enables same-visit clinical decisions

— Early detection enables early and better treatment

Dry Eye Is Primarily an Evaporation Problem

Most dry eye cases are driven by tear film instability — not just tear volume.

Most dry eye cases are driven by tear film instability — not just tear volume

Evaporative (≈50%)

Tears evaporate too quickly from the ocular surface

Evaporative (≈50%)

Tears evaporate too quickly from the ocular surface

Evaporative (≈50%)

Tears evaporate too quickly from the ocular surface

Aqueous Deficient (≈15%)

Insufficient tear production

Aqueous Deficient (≈15%)

Insufficient tear production

Aqueous Deficient (≈15%)

Insufficient tear production

Mixed (≈35%)

Combination of evaporation and low tear production

Mixed (≈35%)

Combination of evaporation and low tear production

Mixed (≈35%)

Combination of evaporation and low tear production

~85% of dry eye cases involve excessive tear evaporation

From Symptoms to Objective Measurement

Based on ocular surface cooling dynamics, a key indicator of tear evaporation

What is measured

Eye surface cooling after each blink

description

View Paper →

What is measured

Eye surface cooling after each blink

description

View Paper →

What it means

Faster cooling = unstable tear film

View Paper →

What it means

Faster cooling = unstable tear film

View Paper →

Why it matters

Enable objective screening decisions

View Paper →

Why it matters

Enable objective screening decisions

View Paper →

This measurement is captured during a standard exam workflow.

Learn how the technology works →

Fits Seamlessly Into Routine Exams

No disruption. No additional chair time.

3. Output → screening result

Validated in clinical studies. Designed for regulatory pathways.

Clinically Validated Measurement

Measured cooling curves show consistent temperature decline across ocular regions

78+ patients clinically tested

— Reproducible measurements across subjects

— Sensitive to tear film dynamics

— Cooling rate differentiates dry eye vs normal eyes

Ongoing Clinical Studies

Scientific & Clinical Recognition

78+ patients clinically tested

Ongoing Clinical Studies

Scientific & Clinical Recognition

78+ patients clinically tested

Ongoing Clinical Studies

Scientific & Clinical Recognition

Enables reliable screening — not subjective assessment

View Clinical Validation →

Available for Early Clinical Access

Pilot programs

Available now for research and early clinical partners.

Request Demo

Research collaborations

Available for academic and clinical research focused on system validation, biomarker development, and translational outcomes.

Upcoming clinical rollout

Broader clinical availability will follow regulatory clearance and expanded validation studies.

Join the waitlist

Pilot programs

Available now for research and early clinical partners.

Request Demo

Research collaborations

Available for academic and clinical research focused on system validation, biomarker development, and translational outcomes.

Upcoming clinical rollout

Broader clinical availability will follow regulatory clearance and expanded validation studies.

Join the waitlist

Pilot programs

Available now for research and early clinical partners.

Request Demo

Research collaborations

Available for academic and clinical research focused on system validation, biomarker development, and translational outcomes.

Upcoming clinical rollout

Broader clinical availability will follow regulatory clearance and expanded validation studies.

Join the waitlist

Screen Every Patient for Dry Eye — in 30 Seconds

Dry Eye Is Common — But Accurate Diagnosis is Poor

Incidence is increasing and many cases are not detected

Problem

Problem

A New Approach to Screening

A New Approach to Screening

Dry Eye Is Primarily an Evaporation Problem

Most dry eye cases are driven by tear film instability — not just tear volume.

Most dry eye cases are driven by tear film instability — not just tear volume

Most dry eye cases are driven by tear film instability — not just tear volume

Evaporative (≈50%)

Evaporative (≈50%)

Evaporative (≈50%)

Aqueous Deficient (≈15%)

Aqueous Deficient (≈15%)

Aqueous Deficient (≈15%)

Mixed (≈35%)

Mixed (≈35%)

Mixed (≈35%)

~85% of dry eye cases involve excessive tear evaporation

From Symptoms to Objective Measurement

Eye surface cooling after each blink

Eye surface cooling after each blink

Faster cooling = unstable tear film

Faster cooling = unstable tear film

Enable objective screening decisions

Enable objective screening decisions

This measurement is captured during a standard exam workflow.

Learn how the technology works →

Fits Seamlessly Into Routine Exams

No disruption. No additional chair time.

1. Capture → 30 sec

1. Capture → 30 sec

1. Capture → 30 sec

2. Analyze → automatic

2. Analyze → automatic

2. Analyze → automatic

3. Output → screening result

3. Output → screening result

3. Output → screening result

Validated in clinical studies. Designed for regulatory pathways.

Clinically Validated Measurement

78+ patients clinically tested

Ongoing Clinical Studies

Scientific & Clinical Recognition

78+ patients clinically tested

Ongoing Clinical Studies

Scientific & Clinical Recognition

78+ patients clinically tested

Ongoing Clinical Studies

Scientific & Clinical Recognition

Enables reliable screening — not subjective assessment

Enables reliable screening — not subjective assessment

Available for Early Clinical Access

Pilot programs

Research collaborations

Upcoming clinical rollout

Pilot programs

Research collaborations

Upcoming clinical rollout

Pilot programs

Research collaborations

Upcoming clinical rollout

Available today for research and pilot deployment, with broader clinical rollout following regulatory clearance.

Available today for research and pilot deployment, with broader clinical rollout following regulatory clearance.

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