Hero Image

Clinically Validated Screening for Dry Eye

Differentiates dry eye from normal eyes using measurable tear film dynamics — in 30 seconds.

Hero Image

Clinically Validated Screening for Dry Eye

Differentiates dry eye from normal eyes using measurable tear film dynamics — in 30 seconds.

Hero Image

Clinically Validated Screening for Dry Eye

Differentiates dry eye from normal eyes using measurable tear film dynamics — in 30 seconds.

What We Have Found

What We Have Found

Cooling patterns differ between dry and healthy eyes

Cooling patterns differ between dry and healthy eyes

Cooling patterns differ between dry and healthy eyes

Automated analysis improves measurement consistency

Automated analysis improves measurement consistency

Automated analysis improves measurement consistency

Regional eye temperature measurements are reproducible

Regional eye temperature measurements are reproducible

Regional eye temperature measurements are reproducible

Key Clinical Findings


 Image
 Image

  • Dry eye eyes show faster cooling rates
  • Strong separation between dry and normal groups
  • Consistent trends across multiple regions
Enables objective screening — not subjective assessment

What We Measure

Measurement is based on ocular surface cooling following each blink
 Image

Study Overview

Study Overview

Participants

78 subjects across dry eye and control groups

Participants

78 subjects across dry eye and control groups

Participants

78 subjects across dry eye and control groups

Protocol

Controlled environment and consistent measurement conditions

Protocol

Controlled environment and consistent measurement conditions

Protocol

Controlled environment and consistent measurement conditions

Environment

Prospective clinical study with standardized measurement protocol

Environment

Prospective clinical study with standardized measurement protocol

Environment

Prospective clinical study with standardized measurement protocol

All measurements were collected under standardized clinical conditions

What This Means for Clinical Practice

Screen for abnormal tear-film dynamics in under 30 seconds

Screen for abnormal tear-film dynamics in under 30 seconds

Reduces reliance on subjective symptoms

Reduces reliance on subjective symptoms

Supports earlier and more consistent clinical assessment

Supports earlier and more consistent clinical assessment

See how ThermOcular fits into your clinic workflow

Scientific Publication

Peer-reviewed research, clinical studies, and patented technology

Published

Ocular Surface Temperature Measurement System

IEEE Access · 2023

Feature Image

First synchronized dual-camera system for automated corneal temperature measurement and tracking

Published

Ocular Surface Temperature Measurement System

IEEE Access · 2023

Feature Image

First synchronized dual-camera system for automated corneal temperature measurement and tracking

Published

Image Registration and Artifact Removal

Journal of Imaging · 2025

Feature Image

Advanced pipeline achieving 96%+ segmentation accuracy with robust artifact handling

Published

Image Registration and Artifact Removal

Journal of Imaging · 2025

Feature Image

Advanced pipeline achieving 96%+ segmentation accuracy with robust artifact handling

Under Review

Cooling Rate as a Biomarker for Dry Eye Disease

Clinical Studies · 2026

Feature Image

Clinical validation of ocular surface cooling rate as an objective biomarker for dry eye detection

Under Review

Cooling Rate as a Biomarker for Dry Eye Disease

Clinical Studies · 2026

Feature Image

Clinical validation of ocular surface cooling rate as an objective biomarker for dry eye detection

5+ publications · 3 studies under review · 1 patent
Journal Articles
Improvements in image registration, segmentation, and artifact removal in ThermOcular imaging system

Journal of Imaging · 2025

[View Paper]


AI-powered IR–visible dual-camera system for measuring and tracking ocular surface temperature

Acta Ophthalmologica · 2024

[View Paper]


A novel system for ocular surface temperature measurement and tracking

IEEE Access · 2023

[View Paper]


Toward precision in ocular surface temperature measurement: improvements in image segmentation

Journal of Computational Vision and Imaging Systems · 2023

[View Paper]


A computational thermal-visual imaging system for automatic cornea temperature tracking

Journal of Computational Vision and Imaging Systems · 2022

[View Paper]

Under Review
Cooling rate as a quantitative biomarker for dry eye disease

Clinical Study · 2026


Regional variations in corneal surface cooling for dry eye diagnosis

Clinical Study · 2026


Validation of the ThermOcular dual thermal–visible imaging system
Clinical Study · 2026

Patent
System and method for imaging, segmentation, temporal and spatial tracking, and analysis of visible and infrared images of ocular surface and eye adnexa

US20210321876A1 · CA3116492A1 · 2021

[View Patent]